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As time passes, environmental stressors and biological aging can disrupt these delicate systems

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In serum, both IL-1 receptors can bind IL-1, thereby regulating the bioavailability of the cytokine

Similar content being viewed by others Introduction The presence of the blood-brain barrier (BBB), a tightly interconnected network of blood vessels and endothelial cells that restricts the entry of foreign particles larger than 100 nm into the brain, poses considerable challenges and complexities in advancing therapeutic strategies for neurodegenerative diseases (NDs) 1