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Tirzepatide (Mounjaro and Zepbound) at the 15 mg dose showed comparable lean-mass loss in pattern but modestly less in proportion (approximately 25% of total weight loss as lean mass

Common genetic variation in GLP1R and insulin secretion in response to exogenous GLP-1 in nondiabetic subjects: a pilot study

Sawada et al

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Para profissionais do varejo farmacutico e da indstria, o avano dessas terapias no representa apenas o crescimento de uma nova categoria de medicamentos

There was a progressive decrease of the proportion of patients at target for each 0.5% increase in baseline HbA1c, ranging from 57.8% for HbA1c 7.5% to 20.8% for HbA1c 10% (p for trend 9.0% with no further decrease, whereas for non-insulin drugs the relationship was continuous without any evidence of plateau 5