Conclusion A better understanding of the pathophysiology of these hormones is of a great interest in order to clarify their burden in emerging diseases (such as obesity) not only for their treatment, but also in order to prevent their appearance and progression
The numbing effect lasts about 60 to 90 seconds, which is more than enough time to complete the injection
doi: 10.2337/diabetes.53.9.2397 36 JainMCarlsonGCookWMorrowLPetroneMWhiteNEet al
"GI AEs typically occur during initiation and uptitration, appearing as transient, mild-to-moderate symptoms." Laura Schalliol, PharmD, BCACP, BCGP, Professor of Pharmacy Practice In fact, 94% of adverse events reported in major clinical trials were mild or moderate in severity
Moses RG, Kalra S, Brook D et al (2014) A randomized controlled trial of the efficacy and safety of saxagliptin as add-on therapy in patients with type 2 diabetes and inadequate glycaemic control on metformin plus a sulphonylurea
Long-term extension studies provide helpful insights
