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Of note, the 2022 study [19] was initially identified in our literature search as a 2021 conference abstract and was subsequently published in a journal during preparation of a revision of our manuscript

I take both, and here is what they actually did for a normal fifty-year-old body

Musso G, Saba F, Cassader M, Gambino R

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Dysregulation in these pathways could result in heightened pain sensitivity