It is chemically a true peptide (six amino acids, including two D-amino acid substitutions for stability), so unlike some non-peptide GH secretagogues it is correctly classified in this category
One case-control study found that the presence of periodontitis increases COVID-19 severity by approximately 3.7-fold (71)
Nakamura JL, Phong C, Pinarbasi E, Kogan SC, Vandenberg S, Horvai AE, et al
Its like a software update for the basics: the ability to breathe correctly (which directly affects how you move), create intra-abdominal pressure (which is essential for stabilizing the spine), and control your fingers, toes, and spine
A 2024 npj Aging paper (doi:10.1038/s41514-024-00160-6) demonstrated that adiponectin receptor expression on B cells declines with age, reducing endogenous PEPITEM levels and allowing progressive T-cell infiltration of metabolically active tissues a direct molecular mechanism for inflammaging
Bitters (such as gentian, dandelion root) and Phosphatidylcholine can both help support the billiary system (the liver and gall bladder)
