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doi:10.1002/14651858.CD001423.pub4

There are four established sequential stages of APAP hepatotoxicity, which should be considered upon presentation to clinic

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OSullivan RJ, Arnoult N, Lackner DH, Oganesian L, Haggblom C, Corpet A, Almouzni G, Karlseder J (2014) Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1

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Studies measuring CSF levels of lysosomal hydrolases (involved in the -Syn degradation) found decreased (Balducci et al., 2013b), or increased (Parnetti et al., 2014a) -hexosaminidase, increased cathepsin E (van Dijk et al., 2013b), decreased -mannosidase (Balducci et al., 2011