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In mice with intracranial tumors, Tf-functionalized NPs accumulate effectively in brain tumor tissue, improving drug efficacy and increasing survival rates

Over time, this results in lighter, more radiant, and even-toned skin without bleaching or irritation

These observations imply that direct nose-to-brain transport is responsible for the elevated exendin-4 levels in the brain following intranasal coadministration of L-penetratin/exendin-4

Inflamm Bowel Dis 19:265274 Palmns MSA, Cowan TE, Bomhof MR, Su J, Reimer RA, Vogel HJ, Hittel DS, Shearer J (2014) Low-dose aspartame consumption differentially affects gut microbiota-host metabolic interactions in the diet-induced obese rat

Vol 169 Issue 1, Anne-Laure Bulteau, Luke I

Only three pilot studies have examined BPC-157 in humans, including its use for intraarticular knee pain, interstitial cystitis, and intravenous safety/pharmacokinetics