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NCT03574597 and NCT05556512)

Cognitive complaints in adults have many treatable causes: depression, sleep disorders, thyroid dysfunction, vitamin deficiencies, medication side effects, untreated sleep apnea, hearing loss, and early signs of neurodegenerative disease

To reduce analytic flexibility, teams preregister primary/secondary endpoints, specify covariates, and publish statistical plans

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It also provides joint support and increased energy

Pain rating scales support assessment beyond the standard 010 scale: The 05 scale and Faces scale are for adult patients and may help patients with confusion or communication challenges