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Meta-analyses of the effects of DPP-4 inhibitors, SGLT2 inhibitors and GLP1 receptor analogues on cardiovascular death, myocardial infarction, stroke and hospitalization for heart failure
Subsequent work by Pickart and Margolina identified clusters of affected genes spanning DNA repair, antioxidant defense, ubiquitinproteasome activity, anti-inflammatory signaling, and tissue remodeling [2]
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It is usually caused by damage to the peripheral nerves due to diabetes, infections, injuries, or toxins
"Failure" can mean inadequate weight loss, intolerable side effects, or documented contraindications
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