Not to mention, patent cliffs for injectable GLP-1 agonists are looming, and there are still always going to be those patients who are uncomfortable with the injection delivery
Adults 35 to 65 with systemic fatigue, slower recovery, and declining baseline energy not explained by other causes
This clinical observation is closely mimicked in preclinical rodent studies, in which signs of visceral illness, nausea or conditioned taste aversion after EX4 or GLP-1 treatment have been clearly demonstrated (Thiele et al., 1997, 1998
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These effects are still being explored but add to GLP-1s overall health benefits
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