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doi: 10.1161/hq0202.104001

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With appetite suppressed, this usually requires intentional planning rather than relying on hunger cues alone

The other half consisted of individuals for whom the CPAP machine had either failed or was not tolerated

It can also increase the risk of kidney stones and bone weakening Vision changes and problems, such as sudden nearsightedness (acute myopia) and increased pressure in the eyes Suicidal ideation Birth defects, if used during pregnancy, such as a cleft palate or cleft lip Topiramate drug interactions Topiramate can decrease the effectiveness of certain medications or increase the risk of adverse side effects when taken with some drugs

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