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Ibuprofen exposure has been linked to cytotoxic and genotoxic effects, oxidative stress, and adverse impacts on growth, reproduction, and behavior ( Ibuprofen is commonly detected in surface waters at concentrations ranging from ng/L to g/L

On the one hand, probiotics and prebiotics can restore microbiota diversity, enhance mucin and SCFA production, and lower endotoxin levels, thereby preserving tight-junction integrity and reducing intestinal permeability [156]

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High concentrations and prolonged exposure to ROS causes extensive damage to various integral cellular biomolecules (Figure 1B), including proteins, lipids and nucleic acids, which ultimately hampers multiple cellular functions (88)

Other research indicates consistent hormone support could benefit bone density and cognitive function

Ihara, T