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10.1038/s41392-023-01668-1 108

Results vary, and prescriptions are not guaranteed

Biomarkers of oxidative stress in human epilepsies have recently received further attention

Seek medical advice if you experience: New-onset insomnia or significant sleep disruption that persists after starting B12 supplementation Paradoxical fatigue : Worsening tiredness despite taking B12, which may indicate an underlying condition requiring investigation Neurological symptoms : Tingling, numbness, balance problems, or cognitive changes, which could suggest B12 deficiency or other neurological conditions Mood changes : Anxiety, agitation, or depression that develops or worsens after starting supplementation Palpitations or rapid heartbeat : Though rare, some individuals report cardiovascular symptoms that should be evaluated It's important to note that sleep disturbances may be unrelated to B12 supplementation

Interleukin-1 receptor antagonist: role in biology

Unlike Actilyse, which requires a 60-minute infusion, Metalyse is administered as a single bolus injection, enabling faster treatment and potentially reducing transfer times for patients requiring additional interventions after initial thrombolysis