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Water retention, scale weight, and what to expect Research measuring total body water has found that short-term creatine loading can increase body water by about 2 liters and bump scale weight by around 1 kilogram, so you should treat early scale increases as hydration shifts inside muscular tissue, not fat gain

This reflects the biology of GLP-1 regulation and is not necessarily a failure of the medication

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Their approach was straightforward and practical: Do tirzepatide and semaglutide protect against heart attack, stroke, and death when used in routine care and not in a clinical trial

If you find out youre pregnant and still on semaglutide, dont panic but call your doctor right away