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Nat Commun 13:

Because of that, B12 shots give new life to patients (if lucky to have had a correct diagnosis) who would otherwise be living a round-the-clock nightmare

Some researchers appreciate getting these secondary benefits alongside their tirzepatide protocol, though the amounts included in compounded formulations are typically modest

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Within those trials, results from populations with a BMI of 25 or higher include up to 12% reduction in body weight over 10 weeks, a 321% increase in circulating GLP-1 levels over 16 weeks, and a 22.3% improvement in uncontrolled eating scores