Retatrutide is an investigational once-weekly triple agonist that targets GLP-1, GIP, and glucagon receptors
Frontiers in Endocrinology, 16, 1593334
The first step was designing an analogue of a biological medicine - a hormone called GLP-1, used in treatments for type 2 diabetes and obesity - that was inherently more stable in the harsh environment of the stomach
While it's essential to recognize that the FDA does not endorse off-label use, the demand for Ozempics weight loss magic couldn't be ignored, leading to practitioners across the country taking the obesity fight into their own handsor prescription pads
Laboratory data were extracted at two different points: throughout the baseline period and at the point closest to the index date, since the long baseline period may not reflect the actual value at time of drug initiation
Perry VH, Cunningham C, Holmes C