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Scientists investigate its potential role in cellular signalling, tissue biology, vascular research, and gastrointestinal physiology

The initial papers that established the correlation between IRS activation and increased resistance to antidepressant treatment were published in the 1990s

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At therapeutic doses, healthy livers detoxify NAPQI by phase II conjugation with glutathione (GSH) to form inert mercapturate and cysteine metabolites

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