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Over 68 weeks, patients taking the drug lost 15-20% of their body weight, compared with 2.4% for those taking a placebo in recent clinical trials

References: Benowitz NL (2024): Antihypertensive Agents (Chapter 11)

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Structurally unique GLP-1-based medicines that achieve substantially greater and rapid weight loss may impact musculoskeletal health, providing a rationale for therapeutics that more selectively target adipose tissue loss while preserving muscle mass and strength

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