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A systematic review of 20 RCTs indicated that supplementation with vitamin B and/or vitamin D might be a well-tolerated and effective adjunctive approach for alleviating symptoms of anxiety and depression, depending on patients' nutritional biomarkers and clinical status [40]

Cleavage Under Targets and Release Using Nuclease (CUT&RUN) The CUT&RUN protocol was adopted from the Nature Protocols manuscript by Skene, Henikoff & Henikoff 130,131

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