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Some of the adverse events are serious and some patients reported seeking medical attention for their symptoms, including nausea, vomiting, diarrhea, abdominal pain and constipation

This includes kidney disease, heart failure, and vascular damage

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There was a relatively high incidence of pancreatic hyperplasia and atrophy in all groups of male rats, including the controls, and a lower incidence in all female groups

Meta-analytical evidence has further demonstrated that oxidative stress is consistently increased by herpesvirus infection across multiple tissues and host species infected with different herpesviruses 15

People with type 2 diabetes are more likely than average to develop gout, though its not clear if its the diabetes itself or other common risk factors like obesity and hypertension that explain the connection