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The biggest risk factors include: Baseline MAFLD diagnosis (aHR 2.11) BMI between 30-34 compared to BMI 40+ (aHR 1.93) Pre-existing GERD (aHR 1.80) Female gender (aHR 1.56) [4] Different GLP-1 medications show varying risk levels

A study that poses an important methodological issue on the possible detection bias induced by glucagon-like peptide 1 receptor agonist treatment

Preferred therapy: Insulin remains the gold standard

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It also has warnings for increased blood pressure and heart rate, risk of seizures (especially in those with a history of seizures or eating disorders), potential liver damage, angle-closure glaucoma (a serious eye condition), and increases in blood pressure or heart rate