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doi: 10.1124/mol.63.6.1256

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The first was Phentermine-topiramate ER, sold under Qsymia and made by Californian company Vivus, which leads to an 8.5 per cent weight loss after a year of use

Long-term success depends on choosing a treatment that is well tolerated, clinically appropriate and realistic for each patients lifestyle

A fair number of studies have investigated the relationship between depressive symptoms and the phase angle difference between DLMO and the timing of other rhythmic functions, including sleep ( Even though the molecular and mechanistic underpinnings are yet to be unveiled, the way the clock, sleep and behavior co-exist and co-affect each other seems crucial to balance health and disease [see ( eigen-zeitgeber it isis likely to remain a central player in this framework