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Over-activation of the complement cascade by the SARS-CoV-2 nucleoprotein, via the lectin pathway, resulted in enhanced lung injury in mice 7

The effects of long-term oral benfotiamine supplementation on peripheral nerve function and inflammatory markers in patients with type 1 diabetes: a 24-month, double-blind, randomized, placebo-controlled trial

Reduces inflammation and oxidative stress, which helps maintain the integrity of blood vessel walls, lowering the risk of atherosclerosis

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On the other hand, with IBD-current biologic therapies limited to blocking tumor necrosis factor alpha some theoretical/practical inconsistencies appear