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GLP-1RAs exhibit multifaceted protective effects in SIM by modulating muscle catabolism, inflammation, oxidative stress, and metabolism

SURMOUNT-1 (N=2,539) showed tirzepatide 15 mg produced 22.5% mean body weight reduction at 72 weeks versus 2.4% with placebo in adults with obesity or overweight without diabetes [12]

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Its not a miracle cure, but it offers a thoughtful and biologically aligned alternative to traditional treatments that often come with risks or side effects

Weight loss generally improves markers of cardiovascular risk