10.1530/JOE-19-0385 J
While drug development for sarcopenia is in its infancy, an activin type II receptor antibody (Bimagrumab, Versanis/Eli Lilly), has recently been progressed into a phase-2 clinical trial ( BELIEVE trial ) in obese individuals with the aim to assess the safety and efficacy as monotherapy and in combination with semaglutide
Setmelanotide is also associated with an increase in skin pigmentation in approximately 69-78% of its approved patient population due to activity on MC1R ( Table 1 ) (33, 82)
(melanotus BLEEKER), Schenkel (1901) Dipsadomorphus dendrophilus var
With Glutathione and Antioxidants Includes Glutathione, Vitamin C, and grape seed extract which help protect cells from oxidative stress
The vitamin has low toxicity, so supplementation carries minimal risk, but also likely provides no benefit if stores are adequate