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Additionally, confinement triggers resistance to chemotherapeutics [198] and to programmed cell death triggered by loss of adhesion (aka anoikis) [199] which in turn facilitates breast cancer metastasis [199]

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A 2015 review published in BioMed Research International by Pickart, Vasquez-Soltero, and Margolina provided a comprehensive overview of GHK-Cu as a natural modulator of multiple cellular pathways in skin regeneration