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Acknowledgements We would like to thank the Global Facility Center at Hokkaido University for allowing us to use its mass spectrometer, and especially Ms

9 One should also bear in mind that infectious and inflammatory conditions are associated with an increased production of acute-phase proteins by the liver, and it was estimated that they account significantly for the increased utilization of sulfur amino acids, thus competing with GSH

Higher doses may increase GI side effects (nausea, reduced appetite)

For patients whose primary issue is GH-axis-driven VAT accumulation rather than total caloric excess, tesamorelin may address the root cause more directly

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