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While sterile technique and single-use needles minimize infection risk, any breach in skin integrity creates potential for bacterial entry

If symptoms of low blood sugar occur, eat glucose tablets or gel, corn syrup, honey, or sugar cubes, or drink fruit juice, non-diet soft drink, or sugar dissolved in water to relieve the symptoms

The manufacturer, Novo Nordisk, states that if an unopened pen is stored at room temperature (59 to 86 degrees Fahrenheit), it must be used within 56 days

At a maintenance dose of 2.4mg per week, that same vial lasts just over 2 weeks

To turn this mechanistic insight into a targeted therapy, we developed cartilage-targeting silk fibroin nanoparticles modified with a type II collagen-binding peptide WYRGRL for localized GLP-1RAs delivery (GLP-1RAs@NPs-WYRGRL)

mean age, 15.4 years