Although GLP-1RAs can play a favorable role in improving heart failure based on pre-clinical studies, whereas some clinical evidence relevantly have reported that GLP-1RAs treatment could be associated with adverse heart failure events, eg
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Animal studies have suggested that GLP-1s act on the mesolimbic reward pathways and reduce drug reinforcement in alcohol, nicotine, cocaine, and opioid use disorders
A recently-published study showed that in this age group, compared to placebo, Victoza reduced A1C by an average of 1.3% (from a starting value of 7.8%) over the course of a year when added to metformin
For instance, in November 2023, Lilly Canada, a medicine company, announced that Mounjaro (tirzepatide) is now available in Canada
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