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In experimental models of Alzheimer's disease, GLP-1 receptor agonists have shown promise in reducing amyloid-beta plaque formation and tau protein phosphorylation, two hallmark pathological features of the condition

Wegovy commonly causes nausea, vomiting, and diarrhoea, particularly during dose escalation

Mol Metab (2023) 68:101665

Most patients qualify for therapy if they have a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related health condition such as type 2 diabetes, high blood pressure, high cholesterol, or sleep apnea

This difference is important because overlap symptoms may still occur even when the mechanisms are separate

doi: 10.1016/j.clnu.2020.10.034 143