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With the electrodes already in place in patients brains, the Penn team thought there might be a rare chance to observe the effect of another GLP-1, tirzepatide, on the NAc

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Agitation refers to feeling restless, nervous, or annoyed

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The "Muscle Loss" Concern: Recent 2025-2026 data emphasizes the importance of high protein intake and resistance training on these meds to prevent losing too much lean muscle mass