Theyre worried about your safety or contraindications
Because gallstones are a leading trigger of pancreatitis, gradual weight loss and awareness of gallbladder symptoms are important
But its still a very rare condition, while the other conditions these medications treat are very common, like heart attacks, stroke and kidney disease
This evidence, drawn from several major clinical trials, reveals that GLP-1 RAs like Semaglutide and Tirzepatide can significantly reduce the risk of cardiovascular events, chronic kidney disease, and liver disease while improving conditions like sleep apnea and osteoarthritis
The cAMP/PKA pathway inhibits voltage-gated potassium channels that respond to depolarization, opens and allows K + efflux, repolarizing the cell and allowing increased calcium influx through voltage-dependent calcium channels, resulting in the exocytosis of insulin from -cells (115)
Neves JS, Borges-Canha M, Vasques-Novoa F, et al