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Chronic kidney disease (CKD) CKD is characterized by kidney damage or impaired kidney function that persists for at least 3 months [183]

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Acknowledgements We thank Laura Weilandt and Sonja Bartholom for help with retrieving literature

Patients who use them have no clinical supervision, no baseline labs, no dosing protocol designed for their biology, and no provider to consult if something goes wrong

Referring to the docking modes from earlier studies, the highest-scoring binding modes in these conformations were selected (Fig

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