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Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H
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We have elucidated how malnutrition (especially protein-energy malnutrition and sarcopenia) and systemic inflammation (driven by both the tumor and surgical trauma) create conditions for complications by impairing tissue repair, weakening immune function, and exacerbating catabolism
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In addition, some cell types can utilize transsulfuration and use methionine to biosynthesize cysteine
These complexes are endocytosed via lowdensity lipoprotein receptorrelated protein 1 (LRP1) receptormediated endocytosis, thereby augmenting TLR9 activation and amplifying immune responses [124]
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