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Inhibition of AMP-activated protein kinase protects pancreatic -cells from cytokine-mediated apoptosis and CD8 + T-cellinduced cytotoxicity

Diabetologia 56:25822592 Bailey CJ, Gross JL, Pieters A, Bastien A, List JF (2010) Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial

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This principle of early detection is the same as is demonstrated in mammography for breast cancer or colonoscopy for colon cancer