10.1016/0014-5793(92)81468-2 652 UverskyV
G.SalgadoA
Ferroptosis: A new regulatory mechanism in osteoporosis
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Moreover, iPLA2, a member of the calcium-independent phospholipase A2 family, functions independently of glutathione by cleaving oxidized fatty acid chains from phospholipids, directly removing peroxidized products, effectively detoxifying damaged lipids, and maintaining membrane integrity ( In summary, lipid peroxidation is central in ferroptosis, driven by ROS-mediated oxidative damage to PUFAs in cellular membranes
doi: 10.1073/pnas.0706625104 235 ZhangJZhangFZhaoCXuQLiangCYangYet al