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The nasolabial folds are spared

Mast cells promote blood brain barrier breakdown and neutrophil infiltration in a mouse model of focal cerebral ischemia

doi: 10.1097/prs.0000000000007783 7 SchaverienMVAsaadMSelberJCLiuJChenDNHallMSet al

Here are some widely used options

Generic indicators for loss of resilience before a tipping point leading to population collapse