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Tirzepatide's Recent Market Entry and Dual-Peptide Innovation Tirzepatide introduced a new mechanism in 2022 by simultaneously activating both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptorsa dual-peptide approach not previously available in weight loss therapy

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Categorical variables are expressed as n (%), while continuous variables are presented as median (interquartile range)

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