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The abnormal release of Ca 2+ from the mitochondria to the cytosol leads to the activation of microglia, neuroinflammation, and finally, cell death [29, 93]

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doi: 10.1016/j.exger.2024.112393 203

Doctors may recommend them for adults with: BMI over obesity threshold Weight related health problems Failed diet attempts Metabolic health risks Health Conditions Often Linked to Obesity High blood pressure Sleep apnea Heart disease Type 2 diabetes Joint pain Zepbound or Wegovy for Diabetes This topic often creates confusion

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