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Dysmotility: The Functional Translation of Structure Small intestinal dysmotility in SSc stems from fibrotic remodeling, neuropathy, and loss of interstitial cells of Cajal (ICC)

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also declares personal honoraria/lecture fees from AstraZeneca, Boehringer Ingelheim, Medscape, Napp, Menarini, Novo Nordisk and Rhythm

Immunoglobulins protect your gut barrier

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The strong correlations among these key substances are consistent with the hypothesis that ESC may influence the microbiota-gut-brain axis, potentially associated with depressive-like behaviors via the Bacteroides barnesiae /sphingolipid metabolism pathway