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This suggests that while GLP-1RAs may not outperform metformin in managing hormone levels, they are still beneficial in populations not already treated with metformin 23,24,25,26

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Those who preserve their skeletal muscleor better yet, add musclewhile losing fat will see less of a reduction in their basal metabolic rate than those who lose muscle, Dr

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Continuous stimulation has been theorized to lead to receptor desensitization, whereas intermittent signaling may preserve responsiveness