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Spirulina platensis , a blue-green microalga, is known for its antioxidant, anti-inflammatory, and lipid-lowering properties

The complete absence of human safety data for neurological applications, particularly long-term use affecting mental health, represents a critical knowledge gap

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Fourth, although the sample size achieved the necessary statistical power to support the results, future studies should include larger sample sizes to analyze cohorts and corroborate the directions of the present findings

After treatment, brain tissues were harvested and evaluated for oxidative stress biomarkers (8-OHdG, MDA, GPx, GSH, GST, SOD), pro-inflammatory cytokines (MPO, NF-B, TNF-), ion transport enzymes (Na/K ATPase, Ca ATPase), neurotransmitter levels (dopamine, serotonin, AChE), and the apoptotic marker caspase-3

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