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For broader context, MOTS-c belongs to the same family of mitochondrial peptides as Humanin, another MDP being studied for its protective role in aging and cellular stress

Oxid Med Cell Longev 2019:9613090 Szarka A, Tomasskovics B, Banhegyi G (2012) The ascorbate-glutathione-alpha-tocopherol triad in abiotic stress response

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Preclinical studies have demonstrated that PEG-MGF promotes myoblast proliferation, delays satellite cell differentiation, and increases the number of proliferating muscle precursor cells available for fiber repair a mechanistically distinct profile from IGF-1 LR3 or DES(1-3) IGF-1, which more directly stimulate protein synthesis in committed myotubes

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