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This allows oxygen tension and pH in the microenvironment to restore to normal

During acute stress, cortisol production rises temporarily to provide the energy and resources needed to deal with the stressor

(as sodium ascorbate)

So theres definitely real-world evidence of a mortality benefit to these medications. And because the drugs can reduce the risk of serious health issues from untreated diabetes, they can improve lifespan in people with that condition, or prediabetes, as well

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