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Patients using oral contraceptives should use a non-oral or backup contraceptive method for 4 weeks after initiating Zepbound and for 4 weeks after each dose increase, as the medication may delay gastric emptying and affect absorption of oral medications

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It has encouraged anyone hospitalised with acute pancreatitis suspected to be related to taking these drugs to report it to the Yellow Card scheme

However, Bbs5 / mice exhibited a striking increase in eWAT monocytes (Figure 3D)

Severe allergic reactions including Stevens-Johnson syndrome affect less than 1% of users but can be fatal, typically appearing as widespread skin blistering within 1-3 weeks of starting treatment

The biggest dietary offenders are alcohol, ultra processed foods, and added sugar