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Prescription medications like opioids and antibiotics are known triggers for MCAS, but even something as commonplace as over-the-counter pain relieving NSAIDs, such as aspirin or ibuprofen, can trigger an MCAS episode

The pivotal Phase 2 trial (NCT04881760), published in The New England Journal of Medicine (Jastreboff et al., 2023), enrolled 338 adults with BMI 30 or higher

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demonstrated reduced incidence of influenza-like illness in elderly individuals receiving NAC (130)