These drugs include: Semaglutide (Wegovy, Ozempic) Tirzepatide (Mounjaro) Liraglutide (Saxenda) Common GLP1 side effects: Nausea Vomiting Diarrhoea or constipation Bloating Stomach pain Headaches Fatigue In the STEP 1 trial, participants using semaglutide 2.4 mg (Wegovy) reported the following during the first weeks: Nausea (44.2%) Diarrhoea (29.5%) Vomiting (24.2%) Constipation (23.4%) Most symptoms subsided after the dose-titration phase
Patients often experience hypermobility, joint instability, chronic pain, and can have significant gastrointestinal (GI) issues
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Crucial role of the melanocortin receptor MC1R in experimental colitis
This has been tentatively associated with various metabolic consequences
It acts anti-inflammatory, antioxidant, and protective improving skin condition, hair density, and supporting the regeneration of the whole body