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Research Highlights Animal Studies : Genetically obese rats treated with AOD-9604 showed significant fat loss, confirming its lipolytic effect via 3-adrenergic pathways

8 References Noctor, G., Mhamdi, A., Chaouch, S., et al

Limosilactobacillus reuteri further promotes CD206+ anti-inflammatory macrophages and robust IL-10 production via activation of the TLR1/2STAT3 axis ( Lactobacillus acidophilus inhibits proinflammatory macrophage polarization by upregulating RapGAP ( Akkermansia muciniphila enhances retinoic acid synthesis in dendritic cells, thereby inducing type 3 innate lymphoid cells (ILC3s) to secrete IL-22, a cytokine critical for mucosal repair (Liu H

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While these findings have generated significant interest, human studies remain limited, making it difficult to draw definitive conclusions about its clinical benefits