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Severe Gastrointestinal Disorders: Individuals with a history of severe gastroparesis (paralyzed stomach) or inflammatory bowel disease must approach this switch with extreme caution, as advanced incretin therapies can exacerbate slow digestion

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More recently, independent researchers also reported that a GLP-1 drug reversed age-related molecular changes across multiple organs in aging mice and improved several measures of physical function, even at doses that produced little change in body weight

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