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When restriction has already been part of the story, adding a medication that suppresses appetite is not a neutral intervention. Gastrointestinal Conditions That Require Caution Because GLP-1 medications slow gastric emptying and affect gut motility, certain GI conditions need special caution

doi: 10.1186/2001-1326-1-10 101 KingP

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Some peptides specifically target the growth and protection of nerve cells

If you are low in Vitamin B12 or have a deficiency anaemia, you will not be creating enough red blood cells and the ones you do make might be defective, being abnormally large